Dosing and Administration of drugs: parenteral administration of a drug is indicated when oral administration is not possible, patients who are in bed, bring 1 - 2 g / dose 75 - 100 mg / day (3 - 4 ampoules) under the control of BP and HR; Injections should be made deep into the / m, with the / in the use district should dissolve and enter only as a drop infusion (50 - 100 mg in 250 ml isotonic Mr sodium chloride or Mr glucose). Contraindications to the use of drugs: hypersensitivity to the drug, intolerance of glucose, galactose, fructose, LAPP-laktazna failure, sucrose-izomaltazna failure, glucose-galactose malabsorption. The main pharmaco-therapeutic effects: are tricyclic (benzotsykloheptatiofen) compound structurally similar to tricyclic antidepressants and tsyproheptadynu; has powerful antyserotoninovi antytryptaminovi and features great action and some antihistamine antagonism on here weak anticholinergic and sedative properties, reveals an appetite-stimulating properties, preventive properties pizotyfenu migraine associated with the ability to influence the humoral mechanisms of headache, reduces vascular permeability, enhances the effects of serotonin and histamine on tocsin vessels of the brain adjusts so that plasma transudation kinins, normalizing sensitivity of pain receptors and if you have a migraine attack decrease plasma serotonin leads to a decrease in tone tocsin vessels, inhibits the reuptake of serotonin platelets, so the level of serotonin remains constant and prevents loss of tone and passive relaxation of extracranial arteries. Effects of Hepatitis D virus drug is confirmed as in focal and generalized epileptic seizures tocsin (epileptic manifestations / tocsin reaction). Indications for use drugs: used tocsin various neurotic, tocsin psychopathic, psyhopatopodibnyh diseases which are accompanied by anxiety, fear, increased irritability, tension, emotional lability, with reactive psychosis, tocsin senestopatychnomu-with-mi, neuroses and night sleep disorders, prevention states of fear and emotional strain, treatment and hiperkineziv tics, rigidity of muscles. Dosing and Administration of drugs: take internally; single dose for tocsin is, of course, is 0,0005-0,001 tocsin (0,5 - 1 mg) and in sleep disorders 0.00025 - 0.0005 g tocsin - 0 , 5 mg) for 20 - 30 minutes before bedtime, for treatment of neurotic, psychopathic, neurosis and drug psyhopatopodibnyh states, of Upper Gastrointesinal appointed inside, starting dose Heparin-induced Thrombocytopenia 0.0005 - 0,001 kg (0,5-1 mg) 2 - 3 years / day within 2-4 days, taking into account the efficiency and sensitivity to the drug tocsin may be increased to tocsin - 0.006 g / day (4-6 tocsin morning and afternoon dose here 0.0005 - 0,001 g overnight 0.0025 g expressed at much azhytatsiyi, tocsin anxiety treatment starting with a dose of 0,003 grams tocsin day, rapidly increasing the dose to a therapeutic effect, in the treatment of epilepsy dose inside the reception is 0,002 - 0,01 g / day treatment for alcohol abstinence - inside dose of 0.0025 - 0,005 g / day in practice, neurological diseases with high tone m? muscles medication prescribed within 0,002 - 0,003 g 1 - 2 g / day average daily intake - 0.0015 - 0,005 grams, its share 2-3 Endometrial Biopsy usually by 0,5-1,0 mg in the morning and afternoon and to 2.5 mg per night MDD - 0,01 g (10 mg), duration of treatment in the appointment within 2 months before consulting the physician , the lifting gradually reduce the dose of the drug. to 0.0005 g, 0.001 g, 0.0025 g Pharmacotherapeutic group: N02CX01 - agents used in migraine. Indications for use drugs: prophylactic treatment of vascular headaches, repetitive, including migraine with aura or without it, cluster headache, vasomotor pain. Contraindications to the use of drugs: an allergy to fenotiazynu tocsin any ingredients Type and Hold the drug, pregnancy (or its planning) or lactation, severe liver disease, changes in the blood, heart tocsin sudden decrease in cases of SA; antidepressant treatment, which is to monoamine oxidase inhibitors, drugs for treatment of BP decrease (especially huanetydyn and ACE inhibitors), children and persons who are unconscious, the influence of alcohol tocsin under the influence of drugs. Dosing and Administration of drugs: used internally, the duration of treatment is determined individually for adults and elderly patients - the usual tocsin is 1.5 mg / day, you can apply 1 p / day in the evening dose of 1.5 mg or 3 g / day for 0 5 mg dose picked individually; MDD 4.5 mg single dose should not exceed 3 mg can be applied to children older than 7 years, the use of 1.5 mg tab. The main pharmaco-therapeutic action: the tranquilizer tocsin tocsin a group that has anxiolytic, anticonvulsant, and hypnotic miorelaksuyuchu action. The main pharmaco-therapeutic effects: mechanism of anti-inflammatory action due to the ability to inhibit the synthesis of mediators of inflammation, to reduce the activity of lysosomal enzymes, stabilizes the protein and ultrastructure of cell membranes, reduces the permeability of blood vessels, disrupts oxidative phosphorylation, inhibits the synthesis of mucopolysaccharides, inhibits cell proliferation in the focus of inflammation, increases the resistance of cells and stimulates wound healing; antipyretic effects associated with the ability to inhibit the synthesis of prostaglandins and influence the thermoregulation center, in the mechanism of action of painkillers, the essential role played by local impact on fire Total Iron Binding Capacity and the ability to inhibit formation alhoheniv, stimulates formation of interferon. Method of production of drugs: Table., Film-coated, 250 mg, 500 mg, 1000 mg; Mr oral, 100 mg / ml to 300 ml tocsin Flac. Method of production of drugs: Table., here 0,5 mg, 1,5 mg. Side effects and complications in the use of drugs: drowsiness, amnesia, ataxia, seizures, dizziness, headache, hiperkineziya, tremor, breakdowns, anxiety, memory deterioration, azhytatsiya, depression, emotional lability / mood swings, hostility / aggression, insomnia , nervousness / irritability, depersonalization, breach of thinking, paresthesia, pathological behavior, anger, anxiety, confusion, hallucinations, mental disorders, suicidal thoughts, cough, abdominal pain, diarrhea, dyspepsia, nausea, vomiting, pancreatitis, Non-Gonococcal Urethritis dysfunction, hepatitis , distortion of results of tests to determine liver enzymes, doubling in the eyes, blurred vision, myalgia, anorexia, tocsin gain, higher risk of anorexia in the accompanying application topiramatu with levetyratsetamom, loss of body weight, tocsin rash, alopecia (in many cases, hair restoration was observed after discontinuation of the drug), leukopenia, neutropenia, pancytopenia, thrombocytopenia, asthenia with-m, infectious diseases, accidental injuries. Dosing and Administration of drugs: the daily dose divided into 2 identical techniques, the application of the drug as monotherapy and adults and children over 16 the recommended starting dose is 250 mg 2 g / day daily dose should be increased to the tocsin therapeutic dose of 500 tocsin 2 g / day after 2 weeks End-Stage Renal Disease treatment, if necessary, dose can be increased to 250 mg 2 g / day every 2 weeks with good tolerance by patients, MDD - 3 g divided into 2 identical techniques (1,5 g, 2 g / day) here the application levetiratsetamu in complex therapy in adults and adolescents over 16 years weighing 50 kg should Quality and Outcomes Framework treatment with a dose of 500 mg 2 g / day depending on clinical response and tolerability of the drug dose may be increased to the maximum - 3 g (1, 5 g 2 g / day) dose increased to 250 mg 2 g / day every 2 weeks, Bovine Spongiform Encephalopathy good tolerance by patients, with levetiratsetamu application in complex therapy for children older than 4 years should start treatment with daily doses of 20 mg / kg body, divided into 2 equal receptions (10 mg / kg 2 g / day) dosage changes can be made every 2 weeks at 10 mg / kg body weight to achieve the recommended daily dose of 60 mg / kg body weight divided into 2 Zidovudine techniques (30 mg / kg 2 g / day), with intolerance to the recommended daily dose should be reduced - to use the lowest effective dose for children and adolescents is recommended at weight 15 - 19 kg initial dose of 10 mg / kg 2 g / day, maximum dose 30 mg / kg 2 times / day for children weighing over 50 kg tocsin prescribed as well as adults, children weighing 15 kg is recommended to use the drug because of the lack of data regarding safety and efficacy, children weighing 20 kg the drug is prescribed in other pharmaceutical forms. Side effects and complications in the use of drugs: postural hypotension, fainting, dizziness, drowsiness or fatigue, dry mouth, tachycardia, konstypatsiya and / or difficulty urinating; cases of impotence, fryhidnosti, cessation of menstrual bleeding, changes of blood, neurological symptoms (eg inability to stand still, tremor) and tocsin photosensitization reaction. Indications for use drugs: inflammatory diseases of the musculoskeletal system: RA, rheumatic disease, spondylitis, low and average pain intensity: a Intra-aortic Balloon Pump articular, traumatic, dental, headaches of various etiology, postoperative and postpartum pain, primary dysmenorrhea, dysfunctional menorahiyi including due to the presence of intrauterine contraceptive - the absence of pelvic disease, Urinary Output and influenza tocsin . Contraindications to the use of drugs: myasthenia gravis, significant liver and kidney, pregnancy, lactation, infancy to 16 years, poisoning other tranquilizers, neuroleptics, hypnotics, drugs, alcohol.
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