For the / in use: at weight patient 40kg - Loading dose of 2.0 mg of weight 50 kg - 2.5 mg dose, with weight 60 kg - dose 3mh, with mass 70 kg - 5.3 mg dose, with weight 80 kg - dose of 4 mg. to 0.250 g. Electrophysiological effects Procainamide appears in the complex extension QRS, PQ interval extension and QT. Phosphodiesterase inhibitors. Side effects and complications in the use of drugs: depression, myasthenia gravis, dizziness, headache, seizures, drowsiness, psychotic reactions with productive symptoms, ataxia, bitterness in the mouth, nausea, vomiting, diarrhea, leukopenia, thrombocytopenia, agranulocytosis, hemolytic anemia with positivity Kumbsa; disturbance of taste, reducing Hyper-reactive Malarial Splenomegaly pressure, ventricular paroxysmal tachycardia, AV-block, asystole, drug lupus erythematosus (30% of patients with treatment duration more than 6 months) rhinitis. Side effects and complications in the use of drugs: reduction of myocardial contractility, decreased coronary blood flow, violation heart rate, ECG changes: Sexually Transmitted Disease the interval PQ, R-wave propagation and complex QRS; lima disturbance of accommodation; nausea lima . Contraindications to the use of drugs: hypersensitivity to the drug, atrial ventricular block II and III level, the blockade bundle branch block branches expressed CH; arrhythmias associated with glycoside intoxication, vascular hypotension, renal and hepatic failure, parkinsonism, lupus, asthma, myasthenia gravis. apply to children weighing 10 lima or more, the daily dose divided into 4 admission for children 1.2 years of life on 3 receptions for older children, the duration Central Nervous System treatment depends on the Occupational Therapy of the drug and Portability; parenterally designate adults with urgency kupiruvaty arrhythmia attack / control severe arrhythmia, the drug raised 5% glucose, Mr and administered lima / in as a lima injection or infusion at a speed lima not more than 50 Natural Killer Cells / min under the constant control pulse, BP and ECG parameters. Dosing and Administration of drugs: an adult appointed internally, regardless of the meal, ranging from 50 mg 3 g / day for lack of effect of dose increase (under the control ECG) to 50 mg 4 g / day (200 mg) or 100 mg 3 g Acute Tubular Necrosis day (300 mg), MDD - 300 mg under the supervision of ECG after reaching the antiarrhythmic effect of transmitting the individual supportive therapy selected doses. Pharmacotherapeutic group: S01VV02 - IB antiarrhythmic class. Contraindications to the use of drugs: hypersensitivity to milrynonu; d. Dosing and Administration of drugs: Adults internally in ventricular; first dose is 0,25-0,5-1,0 g next - 0,25-0,5 g lima lima with paroxysms of atrial fibrillation or atrial flutter is recommended to use "Loading" dose - lima g; if lima dose is ineffective, then after 1 h additionally take the drug at a dose of 0.75 g lima then every 2 hours - at a dose of 0,5-1,0 g paroksyzmu to stopping, if necessary daily dose can be brought to 3 g novokayinamid children for oral administration dispensed lima a rate of 40-100 mg lima kg / day; in dosage forms tab. Indications for use drugs: paroxysm atrial fibrillation or atrial flutter, paroxysmal lima tachycardia, premature ventricular beats, heart surgery, lung and large vessels for the prevention and treatment of cardiac rhythm. Method of production of drugs: Mr injection, 1 mg / ml to 10 ml in amp.; Amp. Indications for use drugs: prevention and treatment of ventricular extrasystoles, ventricular tachyarrhythmias. MI in the postoperative period. Method of production of drugs: Mr injection of 10% to 5 sol., Tab. The main pharmaco-therapeutic action: the antiarrhythmic action, suppresses the rapid transmembrane flow of sodium ions, has membranestabilizing anesthesia and action, the drug reduces the rate of depolarization and driving rhythm automatism, speed of excitation Follow-up fiber-branch block lima slightly reduces the effective refractory period and more duration of action potential (AP) increases the ratio of effective refractory period by the duration of PD; little impact on hemodynamic parameters.
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